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Healthcare professionals like you are at risk from a serious threat1-4:


Are you at risk?

If you’re a healthcare professional (HCP) like Lisa, you’re at high risk of exposure to hepatitis B.1,4 Learn what Lisa is up against in her quest for protection, because the same may be true for you.

If you’re a healthcare professional (HCP) like Lisa, you’re at high risk of exposure to hepatitis B.1,4 Learn what Lisa is up against in her quest for protection, because the same may be true for you.

The risk of on-the-job exposure to hepatitis B

Hepatitis B is highly infectious, with HCPs experiencing 600,000 to 800,000 potential exposures each year through needlesticks and splashes. HBV can remain highly infectious outside the body for at least 7 days.

Estimated new cases of HBV in the US have risen over a 5-year period5

2.2 Million People May Have Chronic Hepatitis B
11% to 25% of the Population Are Infected
Up to A 114% Increase In Some States Affected by the Opioid and Heroin Epidemics

Hepatitis B exposure can be life-threatening for unprotected HCPs9


The average risk of infection after a needlestick or cut exposure to HBV-infected blood is up to 62%.7


Despite OSHA and CDC guidelines, many risky, splash-creating activities are conducted without the proper personal protective equipment due to perception of low risk.10





Chronic hepatitis B infection can lead to liver damage and liver cancer, resulting in an estimated 5500 HBV-related deaths each year in the US.9

HCP occupational infection risks include hepatitis B, hepatitis C, HIV, and more. Of these, only hepatitis is vaccine-preventable.12,13

Traditional 3-dose HBV vaccines can fall short, leaving HCPs unprotected

Six Month Gap
Only 25%
Up to 30%

HCPs may face the emotional costs of fear of blood contact and exposure to pathogens prior to completion of a 3-dose HBV vaccine or attainment of immunity.16

An effective hepatitis B vaccination strategy at healthcare institutions is a priority—and OSHA agrees

  • OSHA requires that the hepatitis B vaccine be offered to HCPs who have a reasonable expectation of being exposed to blood and body fluids on the job17
  • Healthcare institutions are urged to have electronic documentation of hepatitis B vaccination for all HCPs17
  • Occupationally acquired hepatitis B infection accounts for direct costs to the healthcare system and medical costs for hepatitis B-related illness and complications7
Six Months Graphic

OSHA recommends that HCPs complete a hepatitis B vaccine series before potential exposure, as higher risk has been reported during training, but achieving immunity can take 6 months with traditional HBV vaccines.11,17

1. American Nurses Association’s Needle Stick Prevention Guide. World Health Organization website. guide.pdf. Accessed July 18, 2018. 2. Schillie S, Harris A, Link-Gelles R, Romero J, Ward J, Nelson N. Recommendations of the Advisory Committee on Immunization Practices for use of a hepatitis B vaccine with a novel adjuvant. MMWR Morb Mortal Wkly Rep. 2018;67(15):455-458. 3. Walayat S, Ahmed Z, Martin D, Puli S, Cashman M, Dhillon S. Recent advances in vaccination of non-responders to standard dose hepatitis B virus vaccine. World J Hepatol. 2015;7(24):2503-2509. 4. Than TT, Jo E, Todt D, et al. High environmental stability of hepatitis B virus and inactivation requirements for chemical biocides. J Infect Dis. 2018 Oct 24. doi: 10.1093/infdis/jiy620. [Epub ahead of print]. 5. Centers for Disease Control and Prevention. Viral Hepatitis. Statistics and Surveillance. Accessed September 28, 2018. 6. Kowdley KV, Wang CC, Welch S, Roberts H, Brosgart CL. Prevalence of chronic hepatitis B among foreign-born persons living in the United States by country of origin. Hepatology. 2012;56(2):422-433. 7. Schillie S, Murphy TV, Sawyer M, et al. CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management. MMWR Recomm Rep. 2013;62(RR-10):1-19. 8. Harris AM, Iqbal K, Schillie S, et al. Increases in acute hepatitis B virus infections – Kentucky, Tennessee, and West Virginia, 2006-2013. MMWR Weekly. 2016;65(3):47–50. 9. Centers for Disease Control and Prevention. Hepatitis B. In: Hamborsky J, Kroger A, Wolfe S, eds. Epidemiology and Prevention of Vaccine-Preventable Diseases. 13th ed. Washington, DC: Public Health Foundation; 2015:149-174. Accessed October 16, 2017. 10. Goss L. Splashes & sharps: occupational exposures in the health care setting. Occup Health Saf. 2015;84(4):42,44,46. Accessed July 23, 2018. 11. Mast EE, Weinbaum CM, Fiore AE, et al. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) part II: immunization of adults. MMWR Recomm Rep. 2006;55(RR-16):1-33. 12. Exposure to blood: what healthcare personnel need to know. Centers for Disease Control and Prevention website. Updated July 2003. Accessed October 16, 2017. 13. OSHA Fact Sheet: OSHA’s bloodborne pathogens standard. Occupational Safety and Health Administration website. Accessed July 18, 2018. 14. Williams WW, Lu P-J, O’Halloran, et al. Surveillance of vaccination coverage among adult populations - United States, 2015. MMWR Surveill Summ. 2017;66(11):1-28. 15. Heyward WL, Kyle M, Blumenau J, et al. Immunogenicity and safety of an investigational hepatitis B vaccine with a toll-like receptor 9 agonist adjuvant (HBsAg-1018) compared to a licensed hepatitis B vaccine in healthy adults 40-70 years of age. Vaccine. 2013;31(46):5300-5305. 16. Lee JM, Botteman MF, Nicklasson L, Cobden D, Pashos CL. Needlestick injury in acute care nurses caring for patients with diabetes mellitus: a retrospective study. Curr Med Res Opin. 2005;21(5):741–747. 17. Hepatitis B vaccination protection. Occupational Safety and Health Administration website. Accessed December 13, 2018.